Jack Bauer, famiglia e soci
Kiefer Sutherland – Jack Bauer
Elisha Cuthbert – Kim Bauer
Annie Wersching – Renee Walker
Paul Wesley – Stephen
Claire Geare – Teri
Michael Madsen – James Ricker
Il CTU di New York
Mykelti Williamson – Brian Hastings (Direttore del CTU)
Mary Lynn Rajskub – Chloe O’Brian
Freddie Prinze Jr. – Cole Ortiz
Katee Sackhoff – Dana Walsh
John Boyd – Arlo Glass
Julian Morris – Owen
Il Governo (Impiegati e soci)
Cherry Jones – Presidente Allison Taylor
Chris Diamantopoulos – Rob Weiss
Bob Gunton – Ethan Kanin
Frank John Hughes – Tim Woods
Michael Gaston – Generale David Brucker
Repubblica Islamica del Kamistan
Anil Kapoor – Presidente Omar Hassan
Necar Zadegan – Dalia Hassan
Nazneen Contractor – Kayla Hassan
Akbar Kurtha – Farhad Hassan
T.J. Ramini – Tarin Faroush
Mido Hamada – Samir Mehran
Rami Malek – Marcos Al-Zacar
Hrach Titizian – Nabeel
Navid Negahban – Jamot
Red Square
Jürgen Prochnow – Sergei Bazhaev
David Anders – Josef Bazhaev
Gene Farber – Oleg Bazhaev
Callum Keith Rennie – Vladimir Laitanan
Doug Hutchison – Davros
Federazione Russa
Graham McTavish – Mikhail Novakovich
Joel Bissonnette – Pavel Tokarev
Nick Jameson – Presidente Yuri Suvarov
Insabbiamento del Governo
Gregory Itzin – Charles Logan
Reed Diamond – Jason Pillar
D.B. Sweeney – Mark Bledsoe
Personaggi vari
Benito Martinez – Victor Aruz
Clayne Crowford – Kevin Wade
Jennifer Westfeldt – Meredith Reed
Michael Filipowich – Nick Coughlin
Mare Winningham – Elaine Al-Zacar
Stephen Root – Bill Prady
